Correlation of apparent diffusion coefficient ratio on 3.0 T MRI with prostate cancer Gleason score

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Diffusion-weighted MRI of peripheral zone prostate cancer: comparison of tumor apparent diffusion coefficient with Gleason score and percentage of tumor on core biopsy.

OBJECTIVE The objective of our study was to determine the relationship between the apparent diffusion coefficient (ADC) value on diffusion-weighted imaging (DWI) and Gleason score of prostate cancer and percentage of tumor involvement on prostate core biopsy. MATERIALS AND METHODS We performed a retrospective study of 57 patients with biopsy-proven prostate cancer who underwent endorectal MRI...

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Assessment of Apparent Diffusion Coefficient Values as Predictor of Aggressiveness in Peripheral Zone Prostate Cancer: Comparison with Gleason Score

Purpose. To determine association between apparent diffusion coefficient value on diffusion-weighted imaging and Gleason score in patients with prostate cancer. Methods. This retrospective case series was conducted at Radiology Department of Aga Khan University between June 2009 and June 2011. 28 patients with biopsy-proven prostate cancer were included who underwent ultrasound guided sextant p...

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Prostate MRI: evaluating tumor volume and apparent diffusion coefficient as surrogate biomarkers for predicting tumor Gleason score.

PURPOSE To investigate whether tumor volume derived from apparent diffusion coefficient (ADC) maps (VolumeADC) and tumor mean ADC value (ADCmean) are independent predictors of prostate tumor Gleason score (GS). EXPERIMENTAL DESIGN Tumor volume and GS were recorded from whole-mount histopathology for 131 men (median age, 60 years) who underwent endorectal diffusion-weighted MRI for local stagi...

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Predicting Gleason Scores of Prostate Cancer Using Combined Trace Apparent Diffusion Coefficient and Tumor Volume

Introduction With increasing life expectancy, prostate cancer (PCA) is becoming one of the most common forms of malignancy in men. Clinically, the Gleason Scores (GS) are commonly used to assess the aggressiveness of PCA with grades from 1 to 5. The GS is one of the parameters in a strategy of staging system that predicts prognosis and helps decision of treatment options. Magnetic resonance (MR...

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Relationship between Gleason score and apparent diffusion coefficients of diffusion-weighted magnetic resonance imaging in prostate cancer patients.

INTRODUCTION We assessed the correlation between the apparent diffusion coefficient (ADC) and pathological Gleason score (GS) of prostate cancer patients. METHODS A total of 125 patients who underwent multiparametric magnetic resonance imaging before radical prostatectomy for prostate cancer were included in this study. ADC values were compared with different GS. We used receiver operating ch...

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ژورنال

عنوان ژورنال: European Journal of Radiology Open

سال: 2018

ISSN: 2352-0477

DOI: 10.1016/j.ejro.2018.03.002